Description

Acetaminophen / Codeine Medication Description

Acetaminophen and codeine is a prescription combination pain medication containing acetaminophen and codeine phosphate. It is indicated for the management of mild to moderate pain when treatment with an opioid is appropriate and alternative treatments are inadequate. The combination provides analgesic effects through two different active ingredients. 

Codeine is an opioid analgesic, while acetaminophen is a non-opioid pain reliever and fever reducer. Available tablet strengths can vary by product; commonly labeled formulations contain 300 mg of acetaminophen combined with 15 mg, 30 mg, or 60 mg of codeine phosphate. 

Key Uses

• Management of mild to moderate pain when an opioid is considered appropriate
• Prescription pain management when alternative treatments are inadequate
• Combination analgesic containing acetaminophen and codeine phosphate
• Available in oral tablet formulations 

Important Safety Information

Acetaminophen/codeine carries serious warnings concerning opioid addiction, abuse and misuse, potentially life-threatening respiratory depression, accidental ingestion, and hepatotoxicity. Combining opioids with alcohol, benzodiazepines, or other central nervous system depressants can increase the risk of profound sedation and respiratory depression.

Because the product contains acetaminophen, patients should also avoid taking additional acetaminophen-containing medicines unless advised by a healthcare professional. Excessive acetaminophen exposure can cause severe liver injury, liver failure, and death.

Codeine-containing medicines also have important age-related and pregnancy/breastfeeding precautions. FDA information warns against certain uses in children and notes risks associated with breastfeeding. 

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Acetaminophen/Codeine: Uses, Safety & Medication Information

• What Is Acetaminophen/Codeine?
• What Is Acetaminophen/Codeine Used For?
• Acetaminophen/Codeine Tablets
• Acetaminophen/Codeine Side Effects
• Acetaminophen/Codeine Warnings and Precautions
• Frequently Asked Questions About Acetaminophen/Codeine

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