Description
Primary Uses
Sertraline is FDA-approved for treating:
– Major depressive disorder (depression)
– Obsessive-compulsive disorder (OCD)
– Panic disorder
– Post-traumatic stress disorder (PTSD)
– Social anxiety disorder
– Premenstrual dysphoric disorder (PMDD)
It may also be used off-label for conditions like generalized anxiety disorder or certain eating disorders.
Common Side Effects
Many side effects are mild and often improve over time:
– Nausea, diarrhea, or indigestion
– Insomnia or drowsiness
– Dry mouth
– Headache
– Increased sweating
– Sexual dysfunction (e.g., decreased libido or difficulty with ejaculation/orgasm)
– Fatigue or dizziness
Less common but serious effects can include serotonin syndrome (especially with interacting drugs), increased bleeding risk, or hyponatremia (low sodium levels, more common in older adults).
Dosage and Administration
Typical starting dose for adults is **50 mg once daily**, often increased gradually to 100–200 mg based on response. It can be taken with or without food, morning or evening. For PMDD, it may be dose continuously or only during the luteal phase. Always follow a doctor’s prescription—do not adjust or stop abruptly, as withdrawal symptoms (e.g., dizziness, irritability) can occur.
Important Warnings
– Antidepressants like sertraline may increase suicidal thoughts or behaviors in children, teens, and young adults, especially early in treatment. Also , close monitoring is essential.
– More so , avoid combining with MAO inhibitors, certain pain/migraine meds, or substances that boost serotonin to prevent serotonin syndrome.
– Use caution in pregnancy (linked to potential heart defects in newborns) or while breastfeeding.
– Inform your doctor of all medications to avoid interactions.
This is general information based on reliable sources like Mayo Clinic, MedlinePlus, and NCBI. **I am not a doctor—consult a healthcare professional for personalized advice, diagnosis, or treatment.** If you’re experiencing side effects or have concerns, seek medical help promptly.






